Scourge of Armagon features four new enemies, bringing the total up to nineteen. Quake's new monsters in the mission pack are supposedly minions of Armagon which have been unleashed to fill in the ranks.
| Monster | Health | Attack 1 | Damage | Attack 2 | Damage |
| Gremlin | 80 | Claw | 11-15 | - | - |
| Spike Mine | 200 | Explosion | 200 | - | - |
| Centroid | 300 | Nailgun | 1-15 | Sting | up to 90 |
| Armagon | 2,500 (e), 3,450 (n), 4,120 (h) | Laser Cannons | 18 | Rocket Launchers | up to 105 |